Patrick M Brunner Selected Research

fezakinumab

1/2019	Baseline IL-22 expression in patients with atopic dermatitis stratifies tissue responses to fezakinumab.
1/2018	Efficacy and safety of fezakinumab (an IL-22 monoclonal antibody) in adults with moderate-to-severe atopic dermatitis inadequately controlled by conventional treatments: A randomized, double-blind, phase 2a trial.

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Patrick M Brunner Research Topics

Disease

14	Atopic Dermatitis (Atopic Eczema) 08/2022 - 07/2015
10	Inflammation (Inflammations) 01/2022 - 11/2013
9	Psoriasis (Pustulosis Palmaris et Plantaris) 01/2021 - 07/2015
2	Neoplasms (Cancer) 01/2021 - 01/2021
2	Hyperplasia 01/2018 - 12/2016
1	Atherosclerotic Plaque (Atheroma) 01/2022
1	Aspirin-Induced Asthma 01/2022
1	Hypersensitivity (Allergy) 01/2022
1	Nasal Polyps (Nasal Polyp) 01/2022
1	Asthma (Bronchial Asthma) 01/2022
1	Rhinosinusitis 01/2022
1	Eosinophilia 01/2022
1	COVID-19 01/2021
1	Autoimmune Diseases (Autoimmune Disease) 01/2021
1	Erythema 01/2021
1	Mycosis Fungoides 01/2021
1	Cutaneous T-Cell Lymphoma (Lymphoma, T Cell, Cutaneous) 01/2021
1	Disease Progression 01/2021
1	Severe Acute Respiratory Syndrome 01/2021
1	Blister (Bulla) 11/2020
1	Folliculitis (Sycosis) 04/2020
1	Rosacea (Acne Rosacea) 04/2020
1	Eczema 04/2020
1	Actinic Keratosis 06/2019
1	Pruritus (Itching) 01/2019
1	Skin Diseases (Skin Disease) 01/2017
1	Atherosclerosis 01/2017
1	Lichen Planus (Lichen Ruber Planus) 07/2015
1	Pemphigus (Pemphigus Vulgaris) 05/2015

Drug/Important Bio-Agent (IBA)

6	Proteins (Proteins, Gene)FDA Link 01/2022 - 01/2017
5	Biomarkers (Surrogate Marker)IBA 01/2022 - 01/2016
4	Biological ProductsIBA 01/2022 - 01/2016
4	CytokinesIBA 01/2019 - 07/2015
3	RNA (Ribonucleic Acid)IBA 01/2021 - 11/2020
2	dupilumabIBA 01/2021 - 04/2020
2	SteroidsIBA 01/2021 - 01/2016
2	LigandsIBA 06/2019 - 07/2015
2	ChemokinesIBA 06/2019 - 07/2015
2	Interleukin-22 (IL-22)IBA 01/2019 - 01/2018
2	InterleukinsIBA 01/2019 - 01/2018
2	fezakinumabIBA 01/2019 - 01/2018
2	Interleukin-17 (Interleukin 17)IBA 01/2018 - 07/2015
2	Interleukin-12 (IL 12)IBA 01/2017 - 11/2013
1	abrocitinibIBA 08/2022
1	Janus Kinase 1IBA 08/2022
1	Non-Steroidal Anti-Inflammatory Agents (NSAIDs)IBA 01/2022
1	Immunoglobulin E (IgE)IBA 01/2022
1	Cyclooxygenase 1IBA 01/2022
1	Omalizumab (Xolair)FDA Link 01/2022
1	Aspirin (Acetylsalicylic Acid)FDA LinkGeneric 01/2022
1	Fluorodeoxyglucose F18 (Fludeoxyglucose F 18)FDA Link 01/2022
1	Pharmaceutical PreparationsIBA 01/2022
1	EnzymesIBA 01/2022
1	Immunosuppressive Agents (Immunosuppressants)IBA 01/2021
1	Heat-Shock Proteins (Heat-Shock Protein)IBA 01/2021
1	T-Cell Antigen Receptors (T-Cell Receptor)IBA 01/2021
1	VaccinesIBA 01/2021
1	Interleukin-7 Receptors (Interleukin 7 Receptor)IBA 01/2021
1	Toll-Like Receptors (Toll-Like Receptor)IBA 01/2021
1	Interleukin-23 (Interleukin 23)IBA 01/2021
1	AmphiregulinIBA 11/2020
1	Immunoglobulin A (IgA)IBA 04/2020
1	Protease Inhibitors (Protease Inhibitor)IBA 06/2019
1	LipidsIBA 01/2018
1	Monoclonal AntibodiesIBA 01/2018
1	Kruppel-Like Transcription Factors (Kruppel-Like Factors)IBA 06/2017
1	C-Reactive ProteinIBA 01/2017
1	Chemokine CX3CL1IBA 01/2017
1	CD40 Ligand (CD40L)IBA 01/2017
1	Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)IBA 01/2017
1	Macrophage Colony-Stimulating FactorIBA 01/2017
1	Ustekinumab (CNTO 1275)FDA Link 01/2017
1	Keratin-16 (Keratin 16)IBA 12/2016
1	Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA 07/2015
1	Interleukin-4 (Interleukin 4)IBA 07/2015
1	Interleukin-12 Subunit p40IBA 07/2015
1	CC ChemokinesIBA 07/2015
1	Imiquimod (Aldara)FDA LinkGeneric 07/2015
1	AutoantibodiesIBA 05/2015
1	DesmogleinsIBA 05/2015

Therapy/Procedure

3	Therapeutics 01/2022 - 11/2013
1	Topical Administration 01/2021
1	Lasers (Laser) 01/2021